Evidence synthesis, Secondary research

Please note: 'Evidence synthesis' and 'secondary research' are treated here as meaning the same.


Using scientific methods to summarise knowledge in an area. HTA evidence synthesis usually includes a systematic review (based on a clearly formulated question, using systematic and explicit methods to identify, select and critically appraise relevant research, and to collect and analyse data from the studies included in the review). It may also include meta-analysis (statistical methods to combine research) and economic evaluations based e.g. on decision modeling.

INAHTA Glossary

Research that does not generate primary data but that involves the qualitative or quantitative synthesis of information from multiple primary studies. Examples are literature reviews, meta-analyses, decision analyses and consensus statements.